HIV type 1 strains common in Europe, Africa, and Asia cocirculate in Yemen.
نویسندگان
چکیده
To determine the HIV-1 genetic diversity in Yemen, 19 strains collected from men and women were sequenced in pol and six of those were full genome sequenced; all were phylogenetically analyzed. Using the pol sequence data, nine (47.3%) were subtype B, six (31.6%) subtype C, two (10.5%) subtype D, one strain (5.3%) subtype A, and another (5.3%) a unique recombinant form (URF). Concordant phylogenies were also obtained for the six strains full genome sequenced. Most of the strains were from the capitol, Sana'a (n=16). Five of the C strains clustered with African Cs, and one clustered with the Indian C strains. Of the two subtype D strains, one clustered with Ugandan strains and one with Cameroon. The subtype A strain was similar to a Cameroon variant of subtype A and the URF strain was a recombinant between CRF11, CRF13, and subtype B. The HIV epidemic in Yemen is extremely complex, with strains of HIV-1 that have originated in East and West Africa, Europe, and India.
منابع مشابه
Challenges and Proposed Actions for HIV/AIDS Control among Children in Iran
It is estimated globally 3.2 million children were living with HIV in 2014, that mostly in sub-Saharan Africa. However, the majority of them infected to HIV from their mothers during pregnancy, during delivery or breastfeeding (1). Antiretroviral therapy (ART) use during and after pregnancy is essential for prevention of mother-to-child transmission (PMTCT) of HIV (2). In the absence of any in...
متن کاملNewly affected country: Yemen
Since April 2012, 536 laboratory‐confirmed cases of human infection with Middle East respiratory syndrome coronavirus (MERS‐CoV) have been reported to WHO, including 145 deaths (Figure 1). To date, the affected countries in the Middle East include Jordan, Kuwait, Oman, Qatar, Saudi Arabia (KSA), United Arab Emirates (UAE) and Yemen; in Africa: Egypt and Tunisia; in Europe: France, Germany, Gree...
متن کاملPaleontology, paleogeography and Paleoenvironment of the Paleocene benthic foraminiferal species of Plummer in the Tethys; a review
Forty two Paleocene benthic foraminiferal species of the Midway Formation in the Gulf Coastal Plain of Texas, USA were firstly investigated by Plummer (1927), and its paleogeographic distribution in some other countries in the Tethyan province were recorded: North America (USA, Mexico), South America (Argentina), Europe (North Sea Basin, Spain, France, Italy, Czech Republic, Bulgaria), North Af...
متن کاملRecombination in HIV: an important viral evolutionary strategy.
Human immunodeficiency virus (HIV) is a diploid virus: each virion carries two complete RNA genomic strands. Homologous recombination can occur when a cell is coinfected with two different but related strains. Naturally occurring recombinant HIV strains have been found in infected patients in regions of the world where multiple genotypic variants cocirculate. One recombinant HIV strain has spre...
متن کاملChemokine Receptors as Therapeutic Targets in HIV Infection
Acquired immunodeficiency syndrome (AIDS) evolved into a pandemic in less than a decade since the first reports of a new set of symptoms that included severe opportunistic infections and unusual neoplasms, particularly Kaposi's sarcoma, in homosexual men [1]. Nearly 30 years since the discovery of the causative agent [2, 3], human immunodeficiency virus (HIV) cannot still be eradicated, nor is ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- AIDS research and human retroviruses
دوره 21 7 شماره
صفحات -
تاریخ انتشار 2005